Fig. 7
From: Comparative immunogenicity of preparations of yeast-derived dengue oral vaccine candidate
Characterization of neutralization potency of LTB-scEDIII-induced antibodies. Twofold serial dilutions of heat inactivated immune serum from LTB-scEDIII-immunized mice, collected at d32 after last oral immunization were assessed for their potency to neutralize and inhibit the infectivity of a DENV-1 and b DENV-2 using a FACS-based neutralization assay. The y-axis corresponds to the observed percentage of virus infection. The dotted horizontal line represents 50% infection. The x-axis corresponds to the logarithm of serum dilution. The neutralization assay was performed in triplicates and the values (from a representative experiment of typically three performed) are shown as the mean ± standard deviation