Table 1 Deduced functions of ORFs in abm BGC from S. koyangensis SCSIO 5802

orf(−2)

Potassium uptake protein

TrkA, Streptomyces coelicolor A3(2) (Q53949.2); 88/96

–

–

orf(−1)

Amino acid permease

PlaP, Escherichia coli O157:H7 (P0AA48.1); 21/39

–

–

abmN

rRNA (Uracil-5-)-methyltransferase

RlmD, Acinetobacter baumannii AB307-0294 (B7H018.1); 30/48

–

–

abmI

Transcriptional activator, SARP family

DnrI, Streptomyces peucetius (P25047.1); 35/50

abyI

–

AbmE2

Luciferase-like monooxygenase, α-subunit

LuxA, Photorhabdus luminescens (P23146.1); 24/42

–

–

abmU

Diels–Alderase

YD repeat-containing protein, Streptomyces regensis (KMS84434.1); 41/52

abyU

absU

abmK

4′-Phosphopantetheinyl transferase superfamily (PPTase)

Npt, Nocardia iowensis (A1YCA5.1); 42/54

–

–

abmL

Metallophosphoesterase

GsiA, Salmonella enterica (Q57RB2.2); 46/60

–

–

abmF4

ABC transporter system ATP-binding protein

OppD, Lactococcus lactis (AIS04392.1); 42/73 or OppF, Lactococcus lactis (ABA47382.1); 43/74

abyF4

absF4

abmF3

ABC transporter system substrate-binding protein dependent permease

OppC, Lactococcus lactis (ABA47380.1); 27/63

abyF3

absF3

abmM

Amidohydrolase

Mb2939c, Mycobacterium bovis AF2122/97 (P68916.1); 28/37

–

–

abmF2

ABC transporter system permease

OppB, Lactococcus lactis (ABA47381.1); 27/58

abyF2

absF2

abmF1

ABC transport system substrate-binding protein

OppA, Lactococcus lactis (AAO63469.1); 20/52

abyF1

absF1

abmJ

Aldo/keto reductase

OsI_15387, Oryza sativa Indica Group (A2XRZ0.1); 50/68

–

absJ

abmG

Ferredoxin

Fd-1, Streptomyces griseolus (P18324.3); 58/75

–

absG1

abmV

Cytochrome P450

Vitamin D3 dihydroxylase, Streptomyces griseolus (P18326.2); 55/70

abyV

absV

abmC

TetR regulatory protein

Mce3R, Mycobacterium tuberculosis H37Rv (P95251.2); 33/48

abyC

absC2

AbmE1

Luciferase-like monooxygenase, β-subunit

LuxB, Photorhabdus luminescens (P19840.1); 20/41

abyE

–

abmD

Major facilitator superfamily of transporter

EmrB, Mycobacterium tuberculosis CDC1551 (P9WG88.1); 34/56

abyD

absD

abmA1

Ketoacyl-S-ACP synthase

ChlM, Streptomyces antibioticus (AAZ77702.1); 61/74

abyA1

absA1

abmA2

Glyceryl-S-ACP synthase

ChlD, Streptomyces antibioticus (AAZ77703.1); 61/70

abyA2

absA2

abmA3

Acyl carrier protein

ChlD2, Streptomyces antibioticus (AAZ77704.1); 56/73

abyA3

absA3

abmA4

2-Oxoacid dehydrogenase multienzymes acyltransferase E2 component

ChlD3, Streptomyces antibioticus (AAZ77705.1); 65/76

abyA4

absA4

abmA5

α/β hydrolase fold protein

ChlD4, Streptomyces antibioticus (AAZ77706.1); 51/64

abmA5

absA5

abmT

Type II thioesterase

PikA5, Streptomyces venezuelae (Q9ZGI1.1); 32/45

abyT

–

abmZ

NADPH-dependent flavin reductase

HsaB, Rhodococcus jostii RHA1 (Q0S808.1); 39/57

abyZ

absH1

abmB1

PKS I (module 1: KS, ATa, ACP; module 2: KS, ATp, DH, KR, ACP; module 3: KS, ATa, DH, KR, ACP; module 4: KS, ATa, DH, KR, ACP)

PikA1, Streptomyces venezuelae (Q9ZGI5.1); 54/65

abyB1

absB1

abmB2

PKS I (module 5: KS, ATp, DH, KR, ACP; module 6: KS, ATa, DH, ER, KR, ACP)

PikA2, Streptomyces venezuelae (Q9ZGI4.1); 49/59

abyB2

absB2

abmB3

PKS I (module 7: KS, ATa, ACP)

PikA1, Streptomyces venezuelae (Q9ZGI5.1); 54/64

abyB3

absB3

abmH

LuxR family transcriptional regulator

NreC, Staphylococcus carnosus subsp. carnosus TM300 (Q7WZY4.1); 48/67

abyH

–

orf(+1)

Hypothetical protein

Hypothetical protein; Actinospica acidiphila (WP_033273634.1); 49/58

–

–

orf(+2)

Hypothetical protein

Hypothetical protein, Actinospica acidiphila (WP_033273633.1); 56/67

–

–

orf(+3)

Alcohol dehydrogenase-like protein

TDH, Agrobacterium radiobacter K84 (B9J738.1); 32/53

–

–