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Table 2 Information of the four activators

From: CRISPR/dCas9-mediated transcriptional improvement of the biosynthetic gene cluster for the epothilone production in Myxococcus xanthus

Name

Gene

Location

Amino acid

Function

ω subunit

MXAN_4890

6123084..6123320

78

DNA-directed RNA polymerase subunit omega

α subunit

MXAN_3326

3869058..3870080

340

DNA-directed RNA polymerase subunit alpha

CarQ

MXAN_4088

5034964..5035515

183

RNA polymerase sigma factor

σ54

MXAN_1061

1238621..1240138

505

RNA polymerase sigma-54 factor