Fig. 5

Substrate-binding pockets of DMWf18-543 and DMWf18-558. Surface view of the structures showing the differences in the substrate-binding pockets of DMWf18-543 (a) and DMWf18-558 (b). The substrate-binding pockets are indicated with red dashed lines. Residues of the catalytic triad are shown as stick models in yellow. c Superposition of the surfaces of DMWf18-543 (green) and DMWf18-558 (gray). Leu199 of DMWf18-543 and Ala199 of DMWf18-558 are shown as stick models