Fig. 2

Arrangement of syl gene cluster and biosynthesis modules. Colored boxes represent open reading frames (ORFs) of syl gene cluster (a). Boxes labeled as C, A, and PCP represent condensation, activation, and peptide carrier protein domains of synthetase modules encoded by sylC and sylD, respectively. Circles denote putative β-ketoacyl synthetase (KS), acyl transferase (AT), dehydratase (DH), β-ketoreductase (KR), acyl carrier protein (ACP), and thioesterase (TE) domains of the polyketide-like module, which is also encoded by sylD (b)