Fig. 6
From: Chemical genomic guided engineering of gamma-valerolactone tolerant yeast
Chemical proteomics and ergosterol quantification for Y133 and Y133 pad1Δ and fdc1Δ. Protein abundance changes of Y133 pad1Δ fdc1Δ versus Y133 in the presence of 1% GVL (a, n = 3). Fold change values are presented on the Y-axis. Proteins that had increased abundance in the Y133 pad1Δ fdc1Δ strain compared to Y133 that are annotated to Ergosterol biosynthesis (GO:0006696) are highlighted in green. Proteins that had decreased abundance in the Y133 pad1Δ fdc1Δ strain compared to Y133 that are annotated to Protein folding (GO:0006457) are highlighted in red. Total cellular ergosterol quantification of Y133 pad1Δ fdc1Δ and Y133 grown aerobically ± 1% GVL (b, Mean ± SE, n = 3)