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Fig. 3 | Microbial Cell Factories

Fig. 3

From: Selection, characterization, and thermal stabilization of llama single domain antibodies towards Ebola virus glycoprotein

Fig. 3

Mutations mapped onto the sdAb structure. The ribbon structure is transparent with the CDRs colored red, green and blue for CDR 1, 2, and 3 respectively. The yellow sticks are the canonical disulfide. The orange sticks are the residues that were changed to make the new disulfide. The red sticks are the VE residues near the N-terminus. The green sticks are the other changes made to EBOV-GP-A8-fneg+. Positions that have been changed by mutagenesis are indicated with the IMGT number of the amino acid that was mutated. The base structure (PDB 5LZ0) is a llama sdAb [50]

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