Fig. 2

Trichosporon oleaginosus can metabolize aromatic substrates. Growth (closed circles or triangle, solid lines) and substrate utilization (open circles, dashed lines) data for 1 g/L a glucose, b pHBA, c resorcinol, and d phenol in TOHN media, respectively. The left axis represents OD₆₀₀ while the right axis represents percent substrate remaining in the media. Growth in 1 g/L of carbon is compared to a negative control containing no additional carbon source (closed triangle, solid line). Each panel shows full consumption of the aromatic compound. Cells grown in resorcinol and pHBA have growth rates approaching those grown in glucose, whereas cells grown in phenol had a longer lag phase and a slower growth rate. Substrates were chosen as representative compounds for each funneling pathway shown in Fig. 1. The data in a–d are the mean and error bars are standard deviation of biological replicates (n = 3). Lines are used only for visual aid