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Table 2 Specific activity of enzymes by parent strain S. hygroscopicus var. ascomyceticus FS35 and recombinants in batch cultures

From: Metabolic network model guided engineering ethylmalonyl-CoA pathway to improve ascomycin production in Streptomyces hygroscopicus var. ascomyceticus

Strains

Enzyme activites (U/mg protein)

Hcd

Ccr

FS35

0.25 ± 0.03

0.08 ± 0.01

HA-Hcd

0.49 ± 0.05

0.13 ± 0.01

HA-Ccr

0.27 ± 0.03

0.28 ± 0.03

HA-Hcd-Ccr

0.55 ± 0.05

0.35 ± 0.04

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Microbial Cell Factories

ISSN: 1475-2859

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