Skip to main content
Fig. 2 | Microbial Cell Factories

Fig. 2

From: Metabolic network model guided engineering ethylmalonyl-CoA pathway to improve ascomycin production in Streptomyces hygroscopicus var. ascomyceticus

Fig. 2

Conservation analysis of primary metabolic enzymes of S. coelicolor A3(2) compared with two S. hygroscopicus strains. The proteins involved in the primary metabolic subsystems of the metabolic model iMK1208 of S. coelicolor A3(2) were used as reference for protein conservation analysis of S. hygroscopicus jinggangensis 5008 (S14-shy) and S. hygroscopicus limoneus KCTC 1717 (S16-shyl). a Homology analysis of proteins related to primary metabolism in S. coelicolor A3(2) and S14-shy. The distribution of homologous and non-homologous proteins in the primary metabolic subsystems of the model iMK1208 against S14-shy is shown in the pie chart. The details of the numbers of non-homologous proteins owing isoenzymes or similar function annotation with the strain S14-shy are also listed in the bar of the pie chart. b Comparison of the proteins in different primary metabolic subsystems of the model iMK1208 with those from the strains S14-shy and S16-shyl respectively. Four secondary metabolism subsystems and two primary metabolism subsystems (not including any proteins in model) were not included in this analysis

Back to article page