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Table 1 Biomass (X), lipid accumulation and citric acid production (Cit) of Y. lipolytica grown in nitrogen limited medium on glucose (Glc), glycerol (Glol) or blend of both

From: Substrates and oxygen dependent citric acid production by Yarrowia lipolytica: insights through transcriptome and fluxome analyses

 

Time (h)

Glol0 (g/L)

Glc0 (g/L)

Glolcons (g/L)

Glc0cons (g/L)

X (g/L)

Lipid (%, w/w)

Cit (g/L)

Ycit/substrate (g/g)

a

25.5

48.1

–

9.0

–

5.1

14.5

0.6

0.07

b

161

48.1

–

47.9

–

8.0

4.1

21.8

0.45

a

29

–

50.9

–

11.4

4.2

11.9

1.1

0.10

b

185

–

50.9

–

50.2

7.1

5.2

21.0

0.42

a

43.5

31.1

18.6

13.2

2.3

4.0

11.1

2.7

0.17

b

230

31.1

18.6

31.1

18.6

7.5

3.3

22.9

0.46

a

24.5

18.9

33.0

9.9

1.5

4.5

14.0

0.9

0.08

b

235

18.9

33.0

18.9

31.9

7.1

7.1

21.1

0.42

  1. Values are given for the two situations: (a) the maximum quantity of lipids in DCW was achieved; (b) the maximum quantity of citric acid was produced. Culture conditions: initial pH 6.5, pH ranging between 5.5 and 6.5, incubation temperature T = 28 ± 2 °C