Skip to main content
Fig. 4 | Microbial Cell Factories

Fig. 4

From: Direct expression of active human tissue inhibitors of metalloproteinases by periplasmic secretion in Escherichia coli

Fig. 4

Inhibitory activities of (N-)TIMPs toward MMPs. Semi-quantitative IC50s of N-TIMP-1 were determined as 46, 65, and 57 nM for MMP-1/2/7 respectively; IC50s of N-TIMP-2 were 3, 6, 38, and 72 nM for MMP-1/2/7 and cdMMP-14 respectively; and IC50s of TIMP-2 were 11, 2, 22, and 22 nM for MMP-1/2/7 and cdMMP-14 respectively. Error bars represent standard deviations from two independent measurements

Back to article page