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Table 1 Two-component regulatory systems based on microbial biosensors coupled with bio-adsorption

From: Engineered microbial biosensors based on bacterial two-component systems as synthetic biotechnology platforms in bioremediation and biorefinery

Field of application TCRS Function Host chassis Promoter-reporter Chemical target Detection range (mM) References
Bioremediation ZraSR (also known as HydHG) Biosensor E. coli XL1-blue zraP-gfp-HydG Zinc 0.01–1 [66]
CuSR Biosensor E. coli XL1-blue cusC-gfp-CusR Copper 0.004–1 [25]
ZraSR and CusSR Biosensor coupled with bio-adsorption E. coli XL1-blue zraP-gfp, cusC-gfp Zinc and Copper 0.05–1 [67]
ZraSR Biosensor coupled with bio-adsorption E. coli TOP10 zraP-gfp-ompC Lead 0.3–1 [68]
ZraSR Biosensor coupled with bio-adsorption E. coli XL1-blue zraP-gfp Zinc 0.1–1 [24]
Biorefinery DcuSZ (Chimeric) Biosensor E. coli BL21
(DE3)
ompC-gfp Fumarate 0.1–10 [55]
MalKZ (Chimeric) Biosensor E. coli BL21
(DE3)
ompC-gfp Malate 0.1–10 [56]
AauSZ (Chimeric) Biosensor E. coli BL21
(DE3)
ompC-gfp Acidic amino acid 0.05–10 [57]
Tazl (Chimeric) Biosensor E. coli RU1012 ompC-lacZ Aspartate 0.2–1 [28]