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Table 1 Distribution of the forms of adipic acid at different pH values

From: Adipic acid tolerance screening for potential adipic acid production hosts

Form

Structure

Amount (%)a

pH 4

pH 5

pH 6

pH 7

Undissociated

70.7

15.2

0.5

0.0

Semi-dissociated

28.2

60.6

20.0

2.5

Dissociated

1.1

24.1

79.5

97.5

  1. aAmounts of the three forms of adipic acid was calculated using the Henderson–Hasselbalch equation: pH = pKa + log10([A−]/[HA]). The pKa values, pKa1 = 4.4 and pKa2 = 5.4, are from Pubchem