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Table 1 Production of milbemycins

From: Engineered biosynthesis of milbemycins in the avermectin high-producing strain Streptomyces avermitilis

Strain Milbemycins (mg/l)
A3 A4 D B2 B3 G Total
SAMA13 7.3 ± 5.5 1.4 ± 1.1 1.3 ± 0.9 183.7 ± 3.0 76.0 ± 8.9 21.8 ± 5.1 291.5 ± 12.7
SAMA1M7 8.0 ± 0.6 1.4 ± 0.2 1.0 ± 0.1 193.1 ± 43.1 70.5 ± 7.2 17.7 ± 10.1 291.7 ± 58.0
SAMA1M7ΔD (flask) 156.6 ± 15.8 68.0 ± 1.9 22.5 ± 0.4 ND ND ND 247.1 ± 14.0
SAMA1M7ΔD (fermenter) 278.9 ± 10.0 98.4 ± 5.9 22.4 ± 9.5 ND ND ND 399.7 ± 20.0
  1. ND Not detected