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Fig. 5 | Microbial Cell Factories

Fig. 5

From: Chromosomal position effect influences the heterologous expression of genes and biosynthetic gene clusters in Streptomyces albus J1074

Fig. 5

Relative concentration of aranciamycin in culture media of heterologous aranciamycin producers. dattB—S. albus SAM1(ΔattB)::p412C06; dpseB4—S. albus SAM2(ΔpseB4)::-p412C06; 1-24—S. albus SAM3 (ΔattB·ΔpseB4)::pAHT::p412C06-mutants. Dotted black line corresponds to average production of aranciamycin by transposon mutant strains; dotted red line corresponds to average production of aranciamycin by control strains with one integration site. Strains were grown for 120 h at 28 °C. Relative concentration of aranciamycin was calculated as peak area per gram of dry mass

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