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Fig. 6 | Microbial Cell Factories

Fig. 6

From: Elimination of N-glycosylation by site mutation further prolongs the half-life of IFN-α/Fc fusion proteins expressed in Pichia pastoris

Fig. 6

Pharmacokinetics of IFN-α/Fc fusion proteins. SD rats (n = 3 per group) were intravenously administered a single dose of 30 µg/kg of the indicated samples via the vena caudalis. Blood samples were drawn prior to treatment and at 0.2, 8, 24, 48, 72, 96, 120 and 144 h after the treatment. The serum human IFN-α level was quantified using the CBA Human IFN-α Flex Set. All data are presented here as mean ± standard deviation of the concentrations

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