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Fig. 1 | Microbial Cell Factories

Fig. 1

From: Elimination of N-glycosylation by site mutation further prolongs the half-life of IFN-α/Fc fusion proteins expressed in Pichia pastoris

Fig. 1

Schematic diagram for IFN-α/Fc fusion proteins. The dimer is composed of two molecules of IFN-α joined to dimeric Fc, and the monomer has a single molecule of IFN-α linked to monomeric Fc. Black circles N-glycosylation site in the wild-type IgG1 Fc region; DB disulfide bridges between dimeric Fc; F-hinge full hinge region of IgG1; P-hinge partial hinge with the amino acid sequence of HTCPPCP

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Microbial Cell Factories

ISSN: 1475-2859

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