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Fig. 1 | Microbial Cell Factories

Fig. 1

From: Siropins, novel serine protease inhibitors from gut microbiota acting on human proteases involved in inflammatory bowel diseases

Fig. 1

Multiple sequence alignment of Siropin 1 and 2 with Thermopin (Uniprot accession number Q47NK3R), Miropin (Uniprot accession number G8UQY8), human α-1-antitrypsin (UniProt accession number P01009), B. longum serpin (UniProt accession number Q8G7X7) and Tengpin (UniProt accession number Q8R9P5). The structural elements shown above the alignment were generated using the native α-1-antitrypsin structure (PDB ID: 1QLP) sequence invariant residues between sequences are typed red on a white background and residues conserved within each group are displayed as white letters on a red background. Underlined sequences represent the predicted hinge region (blue) and reactive center loop (yellow). The predicted cleavage site is marked with a double vertical line. P1 and P1′ residues are labeled

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Microbial Cell Factories

ISSN: 1475-2859

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