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Fig. 3 | Microbial Cell Factories

Fig. 3

From: Elucidation of the glycosylation steps during biosynthesis of antitumor macrolides PM100117 and PM100118 and engineering for novel derivatives

Fig. 3

Production of PM100117 (1) and PM100118 (2) derivatives 3–9 in 2,6-DOH biosynthesis gene mutant strains. a UPLC analysis (254 nm) of metabolite production in S. caniferus GUA-06-05-006A wild-type and ΔgonCM, ΔgonD3, ΔgonE and ΔgonR1 deletion mutants. NR: peak non-related to PM100117/18. b Chemical structure of various PM100117/18 analogues

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Microbial Cell Factories

ISSN: 1475-2859

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