Skip to main content
Fig. 2 | Microbial Cell Factories

Fig. 2

From: Biosynthesis of three N-acetylaminosugar-conjugated flavonoids using engineered Escherichia coli

Fig. 2

a Docking of UDP-N-acetylquinovosamine to AtUGT78D2. The side chain of Asp380 of AtUGT78D2 forms a hydrogen bond with the 3-OH of glucose, and the nitrogen in the backbone of Trp359 forms a hydrogen bond with the 4-OH of glucose. The methyl group of the acetamido of UDP-N-acetylquinovosamine interacts hydrophobically with Phe238, Gln381, and Met288. The methyl group at carbon 5 interacts hydrophobically with the backbone of Thr145 and the side chain of Ala146. b Docking of UDP-N-acetylquinovosamine UDP-N-acetylxylosamine The 3- and 4-hydroxy groups of N-acetylxylosamine interact with the side chain of Asp380 and backbone NH group of Trp359 of AtUGT78D2. The methyl group of 2-acetamido group in N-acetylxylosamine was fitted into a hydrophobic pocket formed by Phe378, Gln381, and Met288

Back to article page