Table 1 Identified proteins showing significant changes of abundance in strains with different Pga1 activity
#Spot | Protein | Name | Function |
|---|---|---|---|
101 | Pc12g05640 | Strong similarity to heat shock protein sspB—Aspergillus niger (HSP90) | Protein folding |
105 | Pc22g11240 | HSP70 (nucleotide binding domain), strong similarity to heat shock protein 70 HSP70—Ajellomyces capsulatus | Protein folding |
129 | Pc22g10220 | Strong similarity to dnaK-type molecular chaperone Ssb2—Saccharomyces cerevisiae | Protein folding |
774 | Pc16g11070 | Strong similarity to mitochondrial heat shock protein Hsp60 - Saccharomyces cerevisiae | Protein folding |
681 | Pc22g19060 | Strong similarity to cyclophilin cypB—Aspergillus nidulans | Protein folding |
3 | Pc22g05690 | Strong similarity to hypothetical protein contig12.tfa_1730cg—Aspergillus fumigatus [Protein containing PH domain (pleckstrin homology domain)] | Signal transduction |
198 | Pc22g17420 | Strong similarity to hypothetical protein contig_1_153_scaffold_12.tfa_500cg—Aspergillus nidulans (Protein containing ankyrin repeat and von Willebrand factor type A (vWFA) domains) | Signal transduction |
562 | Pc22g01260 | Strong similarity to small G-protein Gsp1—Candida albicans (Ran small GTPase) | Signal transduction |
92 | Pc16g11860 | Strong similarity to catalase R catR—Aspergillus niger | Response to oxidative stress |
600 | Pc22g25220 | Strong similarity to 1,4-benzoquinone reductase qr—Phanerochaete chrysosporium | Response to oxidative stress |
643 | Pc22g25220 | Strong similarity to 1,4-benzoquinone reductase qr—Phanerochaete chrysosporium | Response to oxidative stress |
175 | Pc18g05320 | Strong similarity to IMP dehydrogenase IMH3—Candida albicans (inosine monophosphate dehydrogenase) | Purine nucleotide metabolic process |
468 | Pc22g20960 | Strong similarity to urate oxidase uaz—Aspergillus flavus | Purine nucleotide metabolic process |
709 | Pc22g19100 | Strong similarity to 5-aminoimidazole-4-carboxamide ribotide transformylase Ade17—Saccharomyces cerevisiae | Purine nucleotide metabolic process |
211 | Pc21g12590 | Similarity to 6-hydroxy-d-nicotine oxidase 6-HDNO—Arthrobacter oxidans | Carbon utilization |
549 | Pc22g24530 | Similarity to hypothetical protein MDB19—Arabidopsis thaliana (Dienelactone hydrolase) | Carbon utilization |
557 | Pc21g10590 | Strong similarity to carbonic anhydrase pca1—Porphyridium purpureum | Carbon utilization |
149 | Pc20g07710 | Sulfate adenylyltransferase | Amino acid metabolism |
332 | Pc22g13130 | Strong similarity to mitochondrial aspartate aminotransferase mAspAT—Mus musculus | Amino acid metabolism |
174 | Pc18g06000 | Strong similarity to pyruvate kinase pkiA—Aspergillus niger | Central carbon metabolism |
773 | Pc13g12450 | Strong similarity to transketolase Tkl1—Saccharomyces cerevisiae | Central carbon metabolism |
215 | Pc12g03370 | Strong similarity to mitochondrial F1-ATPase alpha-subunit Atp1—Saccharomyces cerevisiae | Oxidative phosphorylation |
229 | Pc21g10070 | Strong similarity to H+-transporting ATP synthase Beta chain—Neurospora crassa | Oxidative phosphorylation |
556 | Pc20g05750 | Strong similarity to levodione reductase like protein An03g05050—Aspergillus niger (short chain dehydrogenase) | Oxidation–reduction process |
782 | Pc13g07960 | Strong similarity to alcohol dehydrogenase ADH like protein An04g02690—Aspergillus niger | Oxidation–reduction process |
781 | Pc18g02110 | Strong similarity to hypothetical protein contig1471_1.tfa_1240 wg—Aspergillus fumigatus (Ribosomal protein S3) | Protein synthesis |
783 | Pc16g10560 | Strong similarity to cytoplasmic ribosomal protein of the large subunit L10—Saccharomyces cerevisiae | Protein synthesis |
349 | Pc13g09680 | Strong similarity to aspartyl proteinase candidapepsin—Candida albicans | Pathogenicity |
359 | Pc13g04170 | Similarity to cell polarity protein tea1p—Schizosaccharomyces pombe | Cell differentiation |
219 | Pc22g04840 | Strong similarity to hypothetical phosphatidyl synthase SPAC22A12.08c—Schizosaccharomyces pombe | Phospholipid biosynthetic process |