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Table 1 Identified proteins showing significant changes of abundance in strains with different Pga1 activity

From: Proteomic analysis of the signaling pathway mediated by the heterotrimeric Gα protein Pga1 of Penicillium chrysogenum

#Spot Protein Name Function
101 Pc12g05640 Strong similarity to heat shock protein sspB—Aspergillus niger (HSP90) Protein folding
105 Pc22g11240 HSP70 (nucleotide binding domain), strong similarity to heat shock protein 70 HSP70—Ajellomyces capsulatus Protein folding
129 Pc22g10220 Strong similarity to dnaK-type molecular chaperone Ssb2—Saccharomyces cerevisiae Protein folding
774 Pc16g11070 Strong similarity to mitochondrial heat shock protein Hsp60 - Saccharomyces cerevisiae Protein folding
681 Pc22g19060 Strong similarity to cyclophilin cypB—Aspergillus nidulans Protein folding
3 Pc22g05690 Strong similarity to hypothetical protein contig12.tfa_1730cg—Aspergillus fumigatus [Protein containing PH domain (pleckstrin homology domain)] Signal transduction
198 Pc22g17420 Strong similarity to hypothetical protein contig_1_153_scaffold_12.tfa_500cg—Aspergillus nidulans (Protein containing ankyrin repeat and von Willebrand factor type A (vWFA) domains) Signal transduction
562 Pc22g01260 Strong similarity to small G-protein Gsp1—Candida albicans (Ran small GTPase) Signal transduction
92 Pc16g11860 Strong similarity to catalase R catR—Aspergillus niger Response to oxidative stress
600 Pc22g25220 Strong similarity to 1,4-benzoquinone reductase qr—Phanerochaete chrysosporium Response to oxidative stress
643 Pc22g25220 Strong similarity to 1,4-benzoquinone reductase qr—Phanerochaete chrysosporium Response to oxidative stress
175 Pc18g05320 Strong similarity to IMP dehydrogenase IMH3—Candida albicans (inosine monophosphate dehydrogenase) Purine nucleotide metabolic process
468 Pc22g20960 Strong similarity to urate oxidase uaz—Aspergillus flavus Purine nucleotide metabolic process
709 Pc22g19100 Strong similarity to 5-aminoimidazole-4-carboxamide ribotide transformylase Ade17—Saccharomyces cerevisiae Purine nucleotide metabolic process
211 Pc21g12590 Similarity to 6-hydroxy-d-nicotine oxidase 6-HDNO—Arthrobacter oxidans Carbon utilization
549 Pc22g24530 Similarity to hypothetical protein MDB19—Arabidopsis thaliana (Dienelactone hydrolase) Carbon utilization
557 Pc21g10590 Strong similarity to carbonic anhydrase pca1—Porphyridium purpureum Carbon utilization
149 Pc20g07710 Sulfate adenylyltransferase Amino acid metabolism
332 Pc22g13130 Strong similarity to mitochondrial aspartate aminotransferase mAspAT—Mus musculus Amino acid metabolism
174 Pc18g06000 Strong similarity to pyruvate kinase pkiA—Aspergillus niger Central carbon metabolism
773 Pc13g12450 Strong similarity to transketolase Tkl1—Saccharomyces cerevisiae Central carbon metabolism
215 Pc12g03370 Strong similarity to mitochondrial F1-ATPase alpha-subunit Atp1—Saccharomyces cerevisiae Oxidative phosphorylation
229 Pc21g10070 Strong similarity to H+-transporting ATP synthase Beta chain—Neurospora crassa Oxidative phosphorylation
556 Pc20g05750 Strong similarity to levodione reductase like protein An03g05050—Aspergillus niger (short chain dehydrogenase) Oxidation–reduction process
782 Pc13g07960 Strong similarity to alcohol dehydrogenase ADH like protein An04g02690—Aspergillus niger Oxidation–reduction process
781 Pc18g02110 Strong similarity to hypothetical protein contig1471_1.tfa_1240 wg—Aspergillus fumigatus (Ribosomal protein S3) Protein synthesis
783 Pc16g10560 Strong similarity to cytoplasmic ribosomal protein of the large subunit L10—Saccharomyces cerevisiae Protein synthesis
349 Pc13g09680 Strong similarity to aspartyl proteinase candidapepsin—Candida albicans Pathogenicity
359 Pc13g04170 Similarity to cell polarity protein tea1p—Schizosaccharomyces pombe Cell differentiation
219 Pc22g04840 Strong similarity to hypothetical phosphatidyl synthase SPAC22A12.08c—Schizosaccharomyces pombe Phospholipid biosynthetic process