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Fig. 6 | Microbial Cell Factories

Fig. 6

From: Characterization of the aurantimycin biosynthetic gene cluster and enhancing its production by manipulating two pathway-specific activators in Streptomyces aurantiacus JA 4570

Fig. 6

Proposed biosynthetic pathway for ATM. a The proposed model for ATM scaffold assembly line driven by the hybrid PKS/NRPS system. KS ketosynthase, AT acyltransferase, ACP acyl carrier protein, DH dehydratase, KR ketoreductase, ER enoylreductase, A adenylation domain, PCP peptidyl carrier protein, C condensation domain, MT methyltransferase domain, E epimerase domain, TE thioesterase domain. b The proposed pathway for the biosynthesis of 2-(2-methylpropyl)malonyl-ACP; c The proposed pathway for the biosynthesis of the nonproteinogenic amino acids building blocks

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