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Fig. 3 | Microbial Cell Factories

Fig. 3

From: Characterization of the aurantimycin biosynthetic gene cluster and enhancing its production by manipulating two pathway-specific activators in Streptomyces aurantiacus JA 4570

Fig. 3

Genetic characterization of artB and artX as positive regulatory genes for ATM biosynthesis. a HPLC analysis of ATM-A production by related recombinants of S. aurantiacus. WT, wild type S. aurantiacus JA 4570; ΔartB, the ΔartB mutant WL02 of S. aurantiacus; ΔartB::pIB139, ΔartB mutant WL02 containing pIB139 as negative control; ΔartB::artB, ΔartB mutant WL02 containing pIB139/artB for complementation; ΔartX, the ΔartX mutant WL03 of S. aurantiacus; ΔartX::pIB139, ΔartX mutant WL03 containing pIB139 as negative control; ΔartX::arX, ΔartX mutant WL03 containing pIB139/artX for complementation; b Comparative analysis of ATM-A production produced by related recomniants of S. aurantiacus. All measurements were conducted in triplicate

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