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Fig. 2 | Microbial Cell Factories

Fig. 2

From: Characterization of a pathway-specific activator of milbemycin biosynthesis and improved milbemycin production by its overexpression in Streptomyces bingchenggensis

Fig. 2

Effect of milR disruption on Milbemycin A3/A4 production. a Genetic organization of mil gene cluster in Streptomyces bingchenggensis BC04 and diagram of milR disruption and complementation constructions. Each arrow indicates a separate open reading frame (ORF) and orientation of transcription. b HPLC analysis of milbemycin A3/A4 production in S. bingchenggensis BC04, BC04/pSET152, ΔmilR, ΔmilR/pSET152::milR. Absorbance at 242 nm was monitored

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Microbial Cell Factories

ISSN: 1475-2859

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