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Fig. 3 | Microbial Cell Factories

Fig. 3

From: Lactococcus lactis carrying the pValac eukaryotic expression vector coding for IL-4 reduces chemically-induced intestinal inflammation by increasing the levels of IL-10-producing regulatory cells

Fig. 3

Colonic cytokines, sIgA and MPO activity levels from BALB/c mice that had TNBS administered intrarectally. a Interleukin 4 (IL-4) levels. b Interleukin 12 (IL-12) levels. c Interferon γ (IFN-γ) levels. d Tumor necrosis factor α (TNF-α) levels. e Interleukin 6 (IL-6) levels. f Mieloperoxidase (MPO) activity levels. g Interleukin 10 (IL-10) levels. h Secretory immunoglobulin A (sIgA) levels. N, negative control; P, positive control; MV, mice that received L. lactis MG1363 (pValac::dts) intragastrically; MI, mice that received L. lactis MG1363 (pValac::dts::IL-4) intragastrically; FV, mice that received L. lactis MG1363 FnBPA+ (pValac::dts) intragastrically; and FI, mice that received L. lactis MG1363 FnBPA+ (pValac::dts::IL-4) intragastrically. Data are shown as mean ± SD (n = 12). p value: *p < 0.05; **p < 0.01; ***p < 0.001

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Microbial Cell Factories

ISSN: 1475-2859

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