TY - JOUR AU - Sventoraityte, J. AU - Zvirbliene, A. AU - Kiudelis, G. PY - 2008 DA - 2008// TI - Immune system alterations in patients with inflammatory bowel disease during remission JO - Medicina (Kaunas) VL - 44 ID - Sventoraityte2008 ER - TY - JOUR AU - Neuman, M. G. PY - 2004 DA - 2004// TI - Signaling for inflammation and repair in inflammatory bowel disease JO - Rom J Gastroenterol VL - 13 ID - Neuman2004 ER - TY - JOUR AU - Reiff, C. AU - Kelly, D. PY - 2010 DA - 2010// TI - Inflammatory bowel disease, gut bacteria and probiotic therapy JO - Int J Med Microbiol VL - 300 UR - https://doi.org/10.1016/j.ijmm.2009.08.004 DO - 10.1016/j.ijmm.2009.08.004 ID - Reiff2010 ER - TY - JOUR AU - Peloquin, J. M. AU - Nguyen, D. D. PY - 2013 DA - 2013// TI - The microbiota and inflammatory bowel disease: insights from animal models JO - Anaerobe VL - 24 UR - https://doi.org/10.1016/j.anaerobe.2013.04.006 DO - 10.1016/j.anaerobe.2013.04.006 ID - Peloquin2013 ER - TY - JOUR AU - Yamamoto, T. PY - 2013 DA - 2013// TI - Nutrition and diet in inflammatory bowel disease JO - Curr Opin Gastroenterol VL - 29 UR - https://doi.org/10.1097/MOG.0b013e32835b9a40 DO - 10.1097/MOG.0b013e32835b9a40 ID - Yamamoto2013 ER - TY - JOUR AU - Holland, N. AU - Dong, J. AU - Garnett, E. PY - 2008 DA - 2008// TI - Reduced intracellular T-helper 1 interferon-gamma in blood of newly diagnosed children with Crohn’s disease and age-related changes in Th1/Th2 cytokine profiles JO - Pedriatr Res VL - 63 UR - https://doi.org/10.1203/PDR.0b013e318163a897 DO - 10.1203/PDR.0b013e318163a897 ID - Holland2008 ER - TY - JOUR AU - Rogy, M. A. AU - Beinhauer, B. G. AU - Reinisch, W. PY - 2000 DA - 2000// TI - Transfer of interleukin-4 and interleukin-10 in patients with severe inflammatory bowel disease of the rectum JO - Hum Gene Ther VL - 11 UR - https://doi.org/10.1089/10430340050111386 DO - 10.1089/10430340050111386 ID - Rogy2000 ER - TY - JOUR AU - Schoffen, J. P. F. AU - Prado, I. M. M. PY - 2011 DA - 2011// TI - Aspectos epidemiológicos e etiológicos da doença de Crohn JO - Revista Saúde e Pesquisa VL - 4 ID - Schoffen2011 ER - TY - JOUR AU - Actis, G. C. AU - Rosina, F. PY - 2013 DA - 2013// TI - Inflammatory bowel disease: an archetype disorder of outer environment sensor systems JO - World J Gastrointest Pharmacol Ther VL - 4 ID - Actis2013 ER - TY - JOUR AU - Chowers, Y. PY - 2013 DA - 2013// TI - Taking Crohn’s disease personally JO - Rambam Maimonides Med J. VL - 4 UR - https://doi.org/10.5041/RMMJ.10111 DO - 10.5041/RMMJ.10111 ID - Chowers2013 ER - TY - JOUR AU - Strober, W. AU - Fuss, I. AU - Mannon, P. PY - 2007 DA - 2007// TI - The fundamental basis of inflammatory bowel disease JO - J Clin Invest. VL - 117 UR - https://doi.org/10.1172/JCI30587 DO - 10.1172/JCI30587 ID - Strober2007 ER - TY - JOUR AU - Paul, W. E. PY - 1991 DA - 1991// TI - Interleukin-4: a prototypic immunoregulatory lymphokine JO - Blood VL - 77 ID - Paul1991 ER - TY - JOUR AU - Luzina, I. G. AU - Keegan, A. D. AU - Heller, N. M. PY - 2012 DA - 2012// TI - Regulation of inflammation by interleukin-4: a review of “alternatives” JO - J Leukoc Biol VL - 92 ID - Luzina2012 ER - TY - JOUR AU - Finkelman, F. D. AU - Urban, J. F. PY - 2001 DA - 2001// TI - The other side of the coin: the protective role of the TH2 cytokines JO - J Allergy Clin Immunol VL - 107 UR - https://doi.org/10.1067/mai.2001.114989 DO - 10.1067/mai.2001.114989 ID - Finkelman2001 ER - TY - JOUR AU - Oliphant, C. J. AU - Barlow, J. L. AU - McKenzie, A. N. PY - 2011 DA - 2011// TI - Insights into the initiation of type 2 immune responses JO - Immunology VL - 134 UR - https://doi.org/10.1111/j.1365-2567.2011.03499.x DO - 10.1111/j.1365-2567.2011.03499.x ID - Oliphant2011 ER - TY - JOUR AU - Gordon, S. AU - Martinez, F. O. PY - 2010 DA - 2010// TI - Alternative activation of macrophages: mechanism and functions JO - Immunity VL - 32 UR - https://doi.org/10.1016/j.immuni.2010.05.007 DO - 10.1016/j.immuni.2010.05.007 ID - Gordon2010 ER - TY - JOUR AU - Li, Z. AU - Zhang, Y. AU - Sun, B. PY - 2011 DA - 2011// TI - Current understanding of Th2 cell differentiation and function JO - Protein Cell VL - 2 UR - https://doi.org/10.1007/s13238-011-1083-5 DO - 10.1007/s13238-011-1083-5 ID - Li2011 ER - TY - JOUR AU - Hogaboam, C. M. AU - Vallance, B. A. AU - Kumar, A. PY - 1997 DA - 1997// TI - Therapeutic effects of interleukin-4 gene transfer in experimental inflammatory bowel disease JO - J Clin Invest. VL - 100 UR - https://doi.org/10.1172/JCI119823 DO - 10.1172/JCI119823 ID - Hogaboam1997 ER - TY - JOUR AU - Opal, S. M. AU - DePalo, V. A. PY - 2000 DA - 2000// TI - Anti-inflammatory cytokines JO - Chest VL - 117 UR - https://doi.org/10.1378/chest.117.4.1162 DO - 10.1378/chest.117.4.1162 ID - Opal2000 ER - TY - JOUR AU - Sanchez-Munoz, F. AU - Dominguez-Lopez, A. AU - Yamamoto-Furusho, J. K. PY - 2008 DA - 2008// TI - Role of cytokines in inflammatory bowel disease JO - World J Gastroenterol VL - 14 UR - https://doi.org/10.3748/wjg.14.4280 DO - 10.3748/wjg.14.4280 ID - Sanchez-Munoz2008 ER - TY - JOUR AU - Xiong, J. AU - Lin, Y. H. AU - Bi, L. H. PY - 2013 DA - 2013// TI - Effects of interleukin-4 or interleukin-10 gene therapy on trinitrobenzenesulfonic acid-induced murine colitis JO - BMC Gastroenterol VL - 13 UR - https://doi.org/10.1186/1471-230X-13-165 DO - 10.1186/1471-230X-13-165 ID - Xiong2013 ER - TY - JOUR AU - Innocentin, S. AU - Guimarães, V. AU - Miyoshi, A. PY - 2009 DA - 2009// TI - Lactococcus lactis expressing either Staphylococcus aureus fibronectin-binding protein A or Listeria monocytogenes internalin A can efficiently internalize and deliver DNA in human epithelial cells JO - Appl Environ Microbiol VL - 75 UR - https://doi.org/10.1128/AEM.00825-09 DO - 10.1128/AEM.00825-09 ID - Innocentin2009 ER - TY - JOUR AU - Pontes, D. AU - Innocentin, S. AU - Carmen, S. PY - 2012 DA - 2012// TI - Production of fibronectin binding protein A at the surface of Lactococcus lactis increases plasmid transfer in vitro and in vivo JO - PLoS One VL - 7 UR - https://doi.org/10.1371/journal.pone.0044892 DO - 10.1371/journal.pone.0044892 ID - Pontes2012 ER - TY - JOUR AU - Carmen, S. AU - Zurita-Turk, M. AU - Lima, F. A. PY - 2013 DA - 2013// TI - A novel interleukin-10 DNA mucosal delivery system attenuates intestinal inflammation in a mouse model JO - Eur J Inflamm VL - 11 ID - Carmen2013 ER - TY - JOUR AU - Guimarães, V. AU - Innocentin, S. AU - Chatel, J. M. PY - 2009 DA - 2009// TI - A new plasmid vector for DNA delivery using lactococci JO - Genet Vaccines Ther VL - 7 UR - https://doi.org/10.1186/1479-0556-7-4 DO - 10.1186/1479-0556-7-4 ID - Guimarães2009 ER - TY - JOUR AU - Dean, D. A. PY - 1997 DA - 1997// TI - Import of plasmid DNA into the nucleus is sequence specific JO - Exp Cell Res VL - 230 UR - https://doi.org/10.1006/excr.1996.3427 DO - 10.1006/excr.1996.3427 ID - Dean1997 ER - TY - JOUR AU - Vacik, J. AU - Dean, B. S. AU - Zimmer, W. E. PY - 1999 DA - 1999// TI - Cell-specific nuclear import of plasmid DNA JO - Gene Ther VL - 6 UR - https://doi.org/10.1038/sj.gt.3300924 DO - 10.1038/sj.gt.3300924 ID - Vacik1999 ER - TY - JOUR AU - Que, Y. A. AU - Francois, P. AU - Haefliger, J. A. PY - 2001 DA - 2001// TI - Reassessing the role of Staphylococcus aureus clumping factor and fibronecting-binding protein by expression in Lactococcus lactis JO - Infect Immun VL - 69 UR - https://doi.org/10.1128/IAI.69.10.6296-6302.2001 DO - 10.1128/IAI.69.10.6296-6302.2001 ID - Que2001 ER - TY - CHAP AU - Reece-Hoyes, J. S. AU - Walhout, A. J. M. ED - Green, M. R. ED - Sambrook, J. PY - 2012 DA - 2012// TI - Cloning and transformation with plasmid vectors BT - Molecular cloning: a laboratory manual PB - Cold Spring Harbor Laboratory CY - Cold Spring Harbor ID - Reece-Hoyes2012 ER - TY - JOUR AU - Langella, P. AU - Loir, Y. AU - Ehrlich, S. D. PY - 1993 DA - 1993// TI - Efficient plasmid mobilization by pIP501 in Lactococcus lactis subsp. lactis JO - J Bacteriol VL - 175 ID - Langella1993 ER - TY - JOUR AU - Cenac, N. AU - Coelho, A. M. AU - Nguyen, C. PY - 2002 DA - 2002// TI - Induction of intestinal inflammation in mouse by activation of proteinase-activated receptor-2 JO - Am J Pathol VL - 161 UR - https://doi.org/10.1016/S0002-9440(10)64466-5 DO - 10.1016/S0002-9440(10)64466-5 ID - Cenac2002 ER - TY - JOUR AU - Ameho, C. K. AU - Adjei, A. A. AU - Harrison, E. K. PY - 1997 DA - 1997// TI - Prophylactic effect of dietary glutamine supplementation on interleukin 8 and tumour necrosis factor α production in trinitrobenzene sulphonic acid induced colitis JO - Gut VL - 41 UR - https://doi.org/10.1136/gut.41.4.487 DO - 10.1136/gut.41.4.487 ID - Ameho1997 ER - TY - JOUR AU - Atreya, R. AU - Mudter, J. AU - Finotto, S. PY - 2000 DA - 2000// TI - Blockade of interleukin 6 trans signaling suppresses T-cell resistance against apoptosis in chronic intestinal inflammation: evidence in crohn disease and experimental colitis in vivo JO - Nat Med VL - 6 UR - https://doi.org/10.1038/75068 DO - 10.1038/75068 ID - Atreya2000 ER - TY - JOUR AU - Jones-Hall, Y. L. AU - Grisham, M. B. PY - 2014 DA - 2014// TI - Immunopathological characterization of selected mouse models of inflammatory bowel disease: comparison to human disease JO - Pathophysiology VL - 21 UR - https://doi.org/10.1016/j.pathophys.2014.05.002 DO - 10.1016/j.pathophys.2014.05.002 ID - Jones-Hall2014 ER - TY - JOUR AU - Hurst, S. M. AU - Wilkinson, T. S. AU - McLoughlin, R. M. PY - 2001 DA - 2001// TI - IL-6 and its soluble receptor orchestrate a temporal switch in the pattern of leukocyte recruitment seen during acute inflammation JO - Immunity VL - 14 UR - https://doi.org/10.1016/S1074-7613(01)00151-0 DO - 10.1016/S1074-7613(01)00151-0 ID - Hurst2001 ER - TY - JOUR AU - Kaplasnki, G. AU - Marin, V. AU - Montero-Julian, F. PY - 2003 DA - 2003// TI - IL-6: a regulator of the transition from neutrophil to monocyte recruitment during inflammation JO - Trends Immunol VL - 24 ID - Kaplasnki2003 ER - TY - JOUR AU - Zhang, Z. AU - Zheng, M. AU - Bindas, J. PY - 2006 DA - 2006// TI - Critical role of IL-17 receptor signaling in acute TNBS-induced colitis JO - Inflamm Bowel Dis VL - 12 UR - https://doi.org/10.1097/01.MIB.0000218764.06959.91 DO - 10.1097/01.MIB.0000218764.06959.91 ID - Zhang2006 ER - TY - JOUR AU - Waldner, M. J. AU - Neurath, M. F. PY - 2014 DA - 2014// TI - Master regulator of intestinal disease: iL-6 in chronic inflammation and cancer development JO - Semin Immunol VL - 26 UR - https://doi.org/10.1016/j.smim.2013.12.003 DO - 10.1016/j.smim.2013.12.003 ID - Waldner2014 ER - TY - JOUR AU - Rovedatti, L. AU - Kudo, T. AU - Biancheri, P. PY - 2009 DA - 2009// TI - Differential regulation of interleukin 17 and interferon gamma production in inflammatory bowel disease JO - Gut VL - 58 UR - https://doi.org/10.1136/gut.2009.182170 DO - 10.1136/gut.2009.182170 ID - Rovedatti2009 ER - TY - JOUR AU - Kitani, A. AU - Fuss, I. J. AU - Nakamura, K. PY - 2000 DA - 2000// TI - Treatment of experimental (trinitrobenzene sulfonic acid) colitis by intranasal administration of transforming growth factor (TGF)-β1 plasmid: TGF-β1-mediated suppression of T helper cell type 1 response occurs by interleukin (IL)-10 induction and IL-12 receptor β2 chain downregulation JO - J Exp Med VL - 192 UR - https://doi.org/10.1084/jem.192.1.41 DO - 10.1084/jem.192.1.41 ID - Kitani2000 ER - TY - JOUR AU - Fuss, I. J. AU - Boirivant, M. AU - Lacy, B. PY - 2002 DA - 2002// TI - The interrelated roles of TGF-β and IL-10 in the regulation of experimental colitis JO - J Immunol VL - 168 UR - https://doi.org/10.4049/jimmunol.168.2.900 DO - 10.4049/jimmunol.168.2.900 ID - Fuss2002 ER - TY - JOUR AU - Cerutti, A. PY - 2008 DA - 2008// TI - The regulation of IgA class switching JO - Nat Rev Immunol VL - 8 UR - https://doi.org/10.1038/nri2322 DO - 10.1038/nri2322 ID - Cerutti2008 ER - TY - JOUR AU - Alexander, K. L. AU - Targan, S. R. AU - Elson, C. O. PY - 2014 DA - 2014// TI - Microbiota activation and regulation of innate and adaptive immunity JO - Immunol Rev VL - 260 UR - https://doi.org/10.1111/imr.12180 DO - 10.1111/imr.12180 ID - Alexander2014 ER - TY - JOUR AU - Levings, M. K. AU - Schrader, J. W. PY - 1999 DA - 1999// TI - IL-4 inhibits the production of TNF-α and IL-12 by STAT6-dependent and -independent mechanisms JO - J Immunol VL - 162 ID - Levings1999 ER - TY - JOUR AU - Neurath, M. F. AU - Weigmann, B. AU - Finotto, F. PY - 2002 DA - 2002// TI - The transcription factor T-bet regulates mucosal T cell activation in experimental colitis and Crohn’s disease JO - J Exp Med VL - 195 UR - https://doi.org/10.1084/jem.20011956 DO - 10.1084/jem.20011956 ID - Neurath2002 ER - TY - JOUR AU - Mullen, A. C. AU - High, F. A. AU - Hutchins, A. S. PY - 2001 DA - 2001// TI - Role of T-bet in commitment of TH1 cells before IL-12-dependent selection JO - Science VL - 292 UR - https://doi.org/10.1126/science.1059835 DO - 10.1126/science.1059835 ID - Mullen2001 ER - TY - JOUR AU - Neurath, M. G. AU - Finotto, F. AU - Glimcher, L. H. PY - 2002 DA - 2002// TI - The role of Th1/Th2 polarization in mucosal immunity JO - Nat Med VL - 8 UR - https://doi.org/10.1038/nm0602-567 DO - 10.1038/nm0602-567 ID - Neurath2002 ER - TY - JOUR AU - Velde, A. A. AU - Verstege, M. I. AU - Hommes, D. W. PY - 2006 DA - 2006// TI - Critical appraisal of the current practice in murine TNBS-induced colitis JO - Inflamm Bowel Dis VL - 12 UR - https://doi.org/10.1097/01.mib.0000227817.54969.5e DO - 10.1097/01.mib.0000227817.54969.5e ID - Velde2006 ER - TY - JOUR AU - Yamamoto, M. AU - Yoshizaki, K. AU - Kishimoto, T. PY - 2000 DA - 2000// TI - IL-6 is required for the development of Th1 cell-mediated murine colitis JO - J Immunol VL - 164 UR - https://doi.org/10.4049/jimmunol.164.9.4878 DO - 10.4049/jimmunol.164.9.4878 ID - Yamamoto2000 ER - TY - JOUR AU - Jin, Y. AU - Lin, Y. AU - Lin, L. PY - 2012 DA - 2012// TI - IL-17/INF-γ interactions regulate intestinal inflammation in TNBS-induced acute colitis JO - J Interferon Cytokine Res VL - 32 UR - https://doi.org/10.1089/jir.2012.0030 DO - 10.1089/jir.2012.0030 ID - Jin2012 ER - TY - JOUR AU - Magan, P. R. AU - Harrington, L. E. AU - O’Quinn, D. B. PY - 2006 DA - 2006// TI - Transforming growth factor-β induces development of the T(H)17 lineage JO - Nature VL - 441 UR - https://doi.org/10.1038/nature04754 DO - 10.1038/nature04754 ID - Magan2006 ER - TY - JOUR AU - Strober, W. AU - Fuss, I. J. AU - Blumberg, R. S. PY - 2002 DA - 2002// TI - The immunology of mucosal models of inflammation JO - Annu Rev Immunol VL - 20 UR - https://doi.org/10.1146/annurev.immunol.20.100301.064816 DO - 10.1146/annurev.immunol.20.100301.064816 ID - Strober2002 ER - TY - JOUR AU - Zurita-Turk, M. AU - Carmen, S. AU - Santos, A. C. PY - 2014 DA - 2014// TI - Lactococcus lactis carrying the pValac DNA expression vector coding for IL-10 reduces inflammation in a murine model of experimental colitis JO - BMC Biotechnol VL - 14 UR - https://doi.org/10.1186/1472-6750-14-73 DO - 10.1186/1472-6750-14-73 ID - Zurita-Turk2014 ER - TY - JOUR AU - Mowat, A. M. AU - Bain, C. C. PY - 2011 DA - 2011// TI - Mucosal macrophages in intestinal homeostasis and inflammation JO - J Innate Immun VL - 3 UR - https://doi.org/10.1159/000329099 DO - 10.1159/000329099 ID - Mowat2011 ER - TY - JOUR AU - Bain, C. C. AU - Mowat, A. M. PY - 2014 DA - 2014// TI - The monocyte-macrophage axis in the intestine JO - Cell Immunol VL - 291 UR - https://doi.org/10.1016/j.cellimm.2014.03.012 DO - 10.1016/j.cellimm.2014.03.012 ID - Bain2014 ER - TY - JOUR AU - Bain, C. C. AU - Mowat, A. M. PY - 2014 DA - 2014// TI - Macrophages in intestinal homeostasis and inflammation JO - Immunol Rev VL - 260 UR - https://doi.org/10.1111/imr.12192 DO - 10.1111/imr.12192 ID - Bain2014 ER - TY - JOUR AU - Mosser, M. D. AU - Edwards, J. P. PY - 2008 DA - 2008// TI - Exploring the full spectrum of macrophage activation JO - Nat Rev Immunol VL - 8 UR - https://doi.org/10.1038/nri2448 DO - 10.1038/nri2448 ID - Mosser2008 ER - TY - JOUR AU - Strober, W. AU - Lúdvíksson, B. R. AU - Fuss, I. J. PY - 1998 DA - 1998// TI - The pathogenesis of mucosal inflammation in murine models of inflammatory bowel disease and Crohn disease JO - Ann Intern Med VL - 128 UR - https://doi.org/10.7326/0003-4819-128-10-199805150-00009 DO - 10.7326/0003-4819-128-10-199805150-00009 ID - Strober1998 ER - TY - JOUR AU - Pontes, D. S. AU - Azevedo, M. S. AU - Chatel, J. M. PY - 2011 DA - 2011// TI - Lactococcus lactis as a live vector: heterologous protein production and DNA delivery systems JO - Protein Expr Purif VL - 79 UR - https://doi.org/10.1016/j.pep.2011.06.005 DO - 10.1016/j.pep.2011.06.005 ID - Pontes2011 ER - TY - JOUR AU - Lyamina, S. V. AU - Kruglov, S. V. AU - Vedenikin, T. Y. PY - 2012 DA - 2012// TI - Alternative reprogramming of M1/M2 phenotype of mouse peritoneal macrophages in vitro with interferon-γ and interleukin-4 JO - Bull Exp Biol Med VL - 152 UR - https://doi.org/10.1007/s10517-012-1572-4 DO - 10.1007/s10517-012-1572-4 ID - Lyamina2012 ER - TY - JOUR AU - Mantovani, A. PY - 2006 DA - 2006// TI - Macrophage diversity and polarization: in vivo veritas JO - Blood VL - 108 UR - https://doi.org/10.1182/blood-2006-05-019430 DO - 10.1182/blood-2006-05-019430 ID - Mantovani2006 ER -