Skip to main content
Fig. 2 | Microbial Cell Factories

Fig. 2

From: Rewiring a secondary metabolite pathway towards itaconic acid production in Aspergillus niger

Fig. 2

Shake flask cultivation of itaconic acid producing A. niger transformants. HPLC analysis of shake flask experiment with AB1.13 itaconic acid producing transformants. Shake flasks were cultivated for 5 days prior to analysis. All strains were analyzed in triplicate. a Production of itaconic acid is compared amongst strains carrying CAD, CAD + MFS, CAD + MTT and CAD + MFS + MTT. Strains AB1.13 #49 and #63 have an fivefold improvement in IA production compared with the parental strain AB1.13 MFS 3.9. b Production of citric acid is compared amongst strains carrying CAD, CAD + MFS, CAD + MTT and CAD + MFS + MTT. The highest IA producers AB1.13 #49 and #63 produce the lowest amount of CA among all strains carrying the full IA biosynthesis cluster

Back to article page