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Table 4 Engineered organisms patented for hyaluronic acid synthesis

From: Genetic basis for hyper production of hyaluronic acid in natural and engineered microorganisms

Host cell

Patent number

Patent date

Escherichia coli

US2014099673 (A1)

10/04/2014

EP2614088 (A1)

17/07/2013

CN102154190 (A)

17/08/2011

Bacillus subtilis

EP2614088 (A1)

17/07/2013

Bacillus megaterium

US2014099673 (A1)

10/04/2014

Streptococcus zooepidemicus

CN103993031 (A)

20/08/2014

Streptococcus thermophilus

JP2012130287 (A)

12/07/2012

Pichia pastoris

CN104212732 (A)

17/12/2014

Yeast cella

JP2007174957 (A)

12/07/2007

Alga cell

EP2914716 (A1)

09/09/2015

Plant cell

PT1951878 (E)

08/06/2015

AU2013201153 (A1)

21/03/2013

US2009260108 (A1)

15/10/2009

 

US2009199311 (A1)

06/08/2009

  1. aYeast specie not informed