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Table 1 Quantitative representation of the training and testing datasets

From: Development of an accurate kinetic model for the central carbon metabolism of Escherichia coli

  

Strain

Extracellular component (Fig. 2)

Intracellular metabolite (Fig. 4)

Intracellular flux (Fig. 5)

# time point

# component

# time point

# metabolite

# time point

# flux

Training dataset

Batch culture [25, 28]

WT

12

3

8

9

6

25a, 10b

∆pykF

10

3

5

9

3

25

∆pgi

18

3

6

9

3

28

∆ppc

23

3

–

–

–

–

  

Dilution rate (D)

Intracellular flux (Fig. 6) # flux

     

Testing dataset

Continuous culture [26]

0.2

38

     

0.4

38

     

0.5

38

     

0.7

38

     
  1. The training datasets were used for model construction. The testing datasets were used for model validation. The numerical values of the experimental data are shown in the MATLAB version of the model: ExpDataForBatchCulture.m, ExpDataForBatchCulture_Flux.m, ExpDataForBatchCulture_IntracellularMetabolite.m, ExpDataForContinuousCulture.m
  2. a25 fluxes for three time points (growth phase)
  3. b10 fluxes for the remaining three time points (stationary phase)
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Microbial Cell Factories

ISSN: 1475-2859

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