Table 4 Expression systems reported for IFNα-2b production

E. coli

Not reported

Intracellular

[2]

E. coli

3 g/L

Refolded from inclusion bodies and purified

[13]

S. cerevisiae

Not reported

Secreted

[3]

B. subtilis

Not reported

Secreted

[4]

P. pastoris

0.45 g/L

Secreted

[5]

P. pastoris

0.60 g/L

Secreted

[6]

L. lactis

2.4 µg/L

Intracellular/secreted

[7]

Y. lipolytica

0.43 g/L

Secreted

[8]

Mouse cells

0.12 g/L

Secreted

[9]

T. reesei

2.4 g/L

Secreted

This work

T. reesei

4.5 g/L

Secreted; protease inhibitors included

This work