Table 3 Bioreactor data and IFNα-2b expression level data (g/L)
Strain # | Deletion | Capacitance (pF/cm) | IFNα-2b level (g/L) | |||||
|---|---|---|---|---|---|---|---|---|
Day 1 | Day 2 | Day 3 | Day 4 | Day 5 | Day 3 | Day 4 | ||
M577 | Parental | n/a | n/a | n/a | n/a | n/a | 0.8 | 0.6 |
M668 | Δsep1 | 5 | 11.5 | 19.9 | 25 | 21.5 | 1.3 | 1.4 |
M671 | Δpep9 | 5 | 9.9 | 15.1 | 20.5 | 21.5 | 0.9 | 1.0 |
M672 | Δpep11 | 4.9 | 6.9 | 12.2 | 17.1 | 20.8 | 0.7 | 0.6 |
M673 | Δslp7 | 2.5 | 6.8 | 13.4 | 19.1 | 21.2 | 1.4 | 2.1 |
M674 | Δamp2 | 4.9 | 7.5 | 13.4 | 18.1 | 22.2 | 2.1 | 2.4 |
Strain # | Deletion | Base consumption (ml) | IFNα-2b level (g/L) | |||||
|---|---|---|---|---|---|---|---|---|
Day 1 | Day 2 | Day 3 | Day 4 | Day 5 | Day 3 | Day 4 | ||
M577 | Parental | 4.8 | 17 | 29 | 48 | 63 | 0.8 | 0.6 |
M668 | Δsep1 | 2 | 17 | 37 | 64 | 68 | 1.3 | 1.4 |
M671 | Δpep9 | 1 | 14 | 27 | 47 | 65 | 0.9 | 1.0 |
M672 | Δpep11 | 0 | 9 | 20 | 38 | 63 | 0.7 | 0.6 |
M673 | Δslp7 | 0 | 8 | 30 | 53 | 76 | 1.4 | 2.1 |
M674 | Δamp2 | 0 | 8 | 27 | 52 | 70 | 2.1 | 2.4 |