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Fig. 6 | Microbial Cell Factories

Fig. 6

From: Integrated omics approaches provide strategies for rapid erythromycin yield increase in Saccharopolyspora erythraea

Fig. 6

Effect of overexpressed genes on erythromycin production, compared to the WT strain. Box plot diagram of erythromycin production by the WT strain and transformants, determined by the microbiological assay; WT: control 1, NRRL2338, A: control 2, WT + pSet152, B: WT + mmsOp1 (pABE60), C: WT + mmsOp1-HA (pABE87), D: WT + ilvB1 (pABE61), E: WT + ilvB1-HA (pABE62), F: WT + mmsOp1-HA + ilvB1-HA (pABE89), G: WT + ilvB1-HA + mmsOp1-HA (pABE88), H: WT + bkdOp (pABE56), I: WT + mmsOp2 (pABE95). Boundaries of the boxes indicate the 1st and the 3rd quartile of the sample populations. Horizontal lines represent the median values and whiskers indicate the highest and lowest values of the results. Asterisks denote statistically significant (p < 0.05) differences between transformants compared to control samples 1 and 2. The data were analysed using SAS/STAT program as described in the “Methods” section

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