Fig. 4From: Integration event induced changes in recombinant protein productivity in Pichia pastoris discovered by whole genome sequencing and derived vector optimizationIllustration of the different cassette-to-cassette orientations of adjacent expression cassettes and the transcription start sites found on them. Cassettes are shown in the (a) head-to-tail, (b) tail-to-tail and (c) head-to-head organizationBack to article page