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Fig. 7 | Microbial Cell Factories

Fig. 7

From: Structural and functional features of self-assembling protein nanoparticles produced in endotoxin-free Escherichia coli

Fig. 7

Nanoparticle biodistribution in normal tissues. a Representative ex vivo images of T22-GFP-H6 nanoparticles uptake in mouse brain, liver, kidney, lung or heart tissue after injection as measured by GFP-emitted fluorescence. b Quantitation of GFP fluorescence expressed as radiant efficiency. Note the negligible level of detected fluorescence, being undistinguishable from the background fluorescence observed in vehicle-treated mice. This was in contrast to the high level of nanoparticle accumulation observed in tumor tissues in the same animals (see Fig. 6)

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