Fig. 5From: ATP citrate lyase mediated cytosolic acetyl-CoA biosynthesis increases mevalonate production in Saccharomyces cerevisiae Comparison of mevalonate production levels by engineered S. cerevisiae strains with and without the PCTR3::PERG12 promoter replacement, and strains with and without ACL, grown in various concentrations of CuSO4. All strains carry IDH1∆ and harbor the pMvaES plasmid. Strains were grown in low [(NH4)2SO4]Back to article page