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Fig. 4 | Microbial Cell Factories

Fig. 4

From: ATP citrate lyase mediated cytosolic acetyl-CoA biosynthesis increases mevalonate production in Saccharomyces cerevisiae

Fig. 4

Time course of mevalonate production (a) and cellular squalene concentrations (b) in engineered strains. Strains are: No symbols represent the unengineered parent strain BY4741; Empty squares represent BY4741 with MvaES genes expressed, JBEI 10569; Emtpy circles represent BY4741 with MvaES and ACLab genes expressed, JBEI 10690; Filled circles represent BY4741 with MvaES and ACLab genes expressed, and the IDH1 gene deleted, JBEI 10691; Crosses represent BY4741 with MvaES, ACLab, and the Y. lipolitica IDH genes expressed JBEI 10692. Strains were grown in low [(NH4)2SO4]

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Microbial Cell Factories

ISSN: 1475-2859

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