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Fig. 1 | Microbial Cell Factories

Fig. 1

From: ATP citrate lyase mediated cytosolic acetyl-CoA biosynthesis increases mevalonate production in Saccharomyces cerevisiae

Fig. 1

Diagram of S. cerevisiae metabolic pathways relevant to this study. Engineered enzymatic steps of native yeast metabolism are IDH1, isocitrate dehydrogenase 1 and ERG12, mevalonate kinase. Non-native engineered enzymatic steps are ACL, ATP citrate lyase of Aspergillus nidulans; mvaE acetoacetyl-CoA synthase and HMG-reductase of Enterococcus faecalis; mvaS, acetoacetyl-CoA thiolase of Enterococcus faecalis

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Microbial Cell Factories

ISSN: 1475-2859

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