Fig. 2From: Characterization and engineering of the biosynthesis gene cluster for antitumor macrolides PM100117 and PM100118 from a marine actinobacteria: generation of a novel improved derivativeIdentification and organization of the PM100117 and PM100118 biosynthetic gene cluster. a Organization of the PM100117 and PM100118 gene cluster. The proposed gene functions are listed in Table 1. b UPLC analysis of PM100117 (1) and PM100118 (2) production in Streptomyces caniferus GUA-06-05-006A wild type (GUA) and mutant gonP1 − Back to article page