Table 1 Recombinant biopharmaceuticals approved in the 1980s
From: Recombinant pharmaceuticals from microbial cells: a 2015 update
Product | Cell factory | Therapeutic indication | Year |
|---|---|---|---|
Humulin | E. coli | Diabetes | 1982 |
Protropin | E. coli | hGH deficiency | 1985 |
Roferon A | E. coli | Hairy cell leukaemia | 1986 |
IntronA | E. coli | Cancer, genital warts and hepatitis | 1986 |
Recombivax | S. cerevisiae | Hepatitis B | 1986 |
Orthoclone OKT3 | Hybridoma cell line | Reversal of acute kidney and transplant rejection | 1986 |
Humatrope | E. coli | hGH deficiency | 1987 |
Activase | CHO | Acute myocardial infarction | 1987 |
Epogen | CHO | Anaemia | 1989 |