Table 1 Average yields of purified antibody fragments from DWP cultures
From: Systematic screening of soluble expression of antibody fragments in the cytoplasm of E. coli
Antibody name | Type | scFv (mg/L) | Fab (mg/L) |
|---|---|---|---|
Humira | IgG1 human | 33 | 5 |
Maa48 | IgG1 human | 4 | 43 |
K2 | IgG1 human | 11 | 26 |
Avastin | IgG1 humanized | – | 3 |
Herceptin | IgG1 humanized | 271 | 50 |
Tysabri | IgG4 humanized | 139 | 25 |
3211 | IgG1 mouse | 19 | 9 |
Mab123 | IgG2 mouse | 6 | 42 |
3M8O | IgA1 human | 86 | 17 |
2R56 | IgE human | 32 | – |
1QLR | IgM human | 26 | 9 |