Engineering cell factories for producing building block chemicals for bio-polymer synthesis

Table 1 Summary of microbial production of polymer building block chemicals from glucose with notable productivities

Monomer	Organism	Titer (g/L)	Yield (mol_product/mol_substrate)	Cultivation time (h)	References
d-Lactic acid	C. glutamicum R ΔldhA/pCRB204	120	1.73	30^a	[19]
	C. glutamicum R LPglc279/pCRB215	195	1.80	80^a	[20]
	E. coli B0013-070B	122	1.69	28	[21]
Succinic acid	C. glutamicum R ΔldhA/pCRA717	146	1.40	46^a	[22]
	C. glutamicum ATCC13032 BOL-3/pAN6-gap	134	1.67	54^a	[23]
	C. glutamicum ATCC13032 SA5	109	1.32	98^a	[24]
	E. coli AFP111/pTrc99A-pyc	99	1.10	76	[25]
	E. coli KJ134	72	1.53	95	[26]
	E. aerogenes ES08 ΔptsG	55	1.32	60	[27]
Putrescine	E. coli XQ52/p15SpeC	24	–	32	[28]
Putrescine	C. glutamicum ^b	19	0.33	34	[29]
Cadaverine	C. glutamicum DAP-16	88	0.50	40	[30]
Cadaverine	E. coli XQ56/p15CadA	9.6	0.07	30	[31]

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