Simulating cyanobacterial phenotypes by integrating flux balance analysis, kinetics, and a light distribution function

Table 1 List of parameters used to simulate the growth and metabolic fluxes of cyanobacteria growing in a cylindrical PBR

Parameters	Significance	Value (range)	Unit	References/notes
K _La	Mass transfer rate of CO₂	10^a (3–15)	h⁻¹	[19]
K _d	Death rate	0.0079	h⁻¹	[46]
Radius	Radius of PBR	60	mm	Similar to the reactor used in Reference [42]
I ₀	Surface light intensity	50	mmol/g/h	Equivalent to ~50 µE/m²/s^b
Km	Half-saturation constant of CO₂ uptake rate	8	µmol/L	[47]
pH	Medium pH	8.0	unitless	BG-11 medium
[X]₀	Initial biomass concentration	0.1	g/L	Equivalent to an OD₇₃₀ of ~0.2
[CO₂]₀	Initial concentration of dissolved CO₂ and HCO₃ ⁻ (in equilibrium with air)	0.53	mmol/L	Estimated^c

^aThe value is used in Figs. 2, 3 and 5; ^ba photosynthesis efficiency of 1.5 % is assumed in Figs. 2, 3 and 5; and ^ccalculation is based on experimental conditions (Additional file 2)

ISSN: 1475-2859