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Fig. 2 | Microbial Cell Factories

Fig. 2

From: Simulating cyanobacterial phenotypes by integrating flux balance analysis, kinetics, and a light distribution function

Fig. 2

Simulations of dynamics of cyanobacterial performance in a 60 mm-radius cylindrical PBR under 50 µE/m2/s surface light intensity. a biomass concentration and dissolved CO2/HCO3 − concentration; b glycogen content in biomass and average specific growth rate; c flux through the PEP carboxylase reaction; d flux through the RuBP carboxylase reaction; e fluxes through the TCA cycle (negative flux means the flux direction is reversed); f ratios of autotrophic, heterotrophic, and resting sub-populations; and g light distribution in the bioreactor as a function of time and relative distance r/R, where r is the local position and R is the radius of the bioreactor. The parameters used for simulation are given in Table 1. Abbreviations of metabolites: 3PG 3-phosphoglycerate, AceCoA acetyl-CoA, CIT citrate, MAL malate, OAA oxaloacetate, PEP phosphoenolpyruvate, and RuBP ribulose-1,5-bisphosphate

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