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Table 1 Haematology and blood biochemistry measurements (mean ± SEM) of spontaneously hypertensive rats (SHR)

From: Effective treatment of hypertension by recombinant Lactobacillus plantarum expressing angiotensin converting enzyme inhibitory peptide

Parameters

PBS

NC8

RLP

WBC (109/L)

5.133 ± 1.935

5.567 ± 0.929

5.400 ± 2.272

RBC (1012/L)

6.810 ± 0.764

6.727 ± 0.748

7.620 ± 0.735

HGB (g/L)

94.33 ± 14.154

102.33 ± 6.658

113.00 ± 10.583

HCT (%)

0.308 ± 0.013

0.320 ± 0.047

0.382 ± 0.034*

MCV (fL)

50.500 ± 0.700

50.000 ± 1.200

50.133 ± 0.351

MCH (pg)

14.133 ± 0.902

15.667 ± 0.757

14.833 ± 0.058

MCHC (g/L)

296.00 ± 30.610

314.00 ± 22.113

295.67 ± 1.155

PLT (109/L)

533.33 ± 59.181

589.33 ± 36.611

661.67 ± 289.096

W-SCR (%)

0.752 ± 0.064

0.607 ± 0.132

0.793 ± 0.159

W-SCC (%)

3.000 ± 0.600

3.133 ± 0.231

4.400 ± 2.193

RDW-SD (fL)

29.000 ± 0.100

29.033 ± 0.379

28.800 ± 0.625

RDW-CV (%)

0.147 ± 0.001

3.147 ± 5.198

0.148 ± 0.009

PDW (fL)

7.500 ± 0.100

7.733 ± 0.451

7.967 ± 0.643

MPV (fL)

6.200 ± 0.100

6.433 ± 0.231

6.700 ± 0.361

P-LCR (%)

0.030 ± 0.011

0.042 ± 0.009

0.047 ± 0.013

UREA (mmol/L)

8.343 ± 1.517

8.340 ± 0.963

7.700 ± 1.908

GLUC (mmol/L)

16.570 ± 2.370

14.300 ± 2.383

15.480 ± 1.019

TCHE (mmol/L)

1.360 ± 0.044

1.333 ± 0.125

1.100 ± 0.050*,#

TG (mmol/L)

1.247 ± 0.025

1.213 ± 0.176

0.750 ± 0.181*,#

  1. The rats were divided into three groups and subjected to either PBS, L. planturm NC8 (NC8) or recombinant Lb.Plantarum NC8 (RLP) treatment for continuous 14 days, and then 5 rats from each group were selected at random at day 14 and the cardiac puncture samples were collected and the following values were measured
  2. WBC white blood cell, RBC red blood cell, HGB haemoglobin, HCT hematocrit, MCV mean corpuscular volume, MCH mean corpuscular haemoglobin, MCHC mean corpuscular haemoglobin concentration, PLT platelet counts, W-SCR lymphocyte percentage, W-SCC absolute value of lymphocyte, PDW platelet distribution width, MPV mean platelet volume, P-LCR platelet large cell ratio, UREA urea nitrogen, GLUC total plasma glucose, TCHE total plasma cholesterol, TG triglyceride
  3. The statistical significance was calculated using one way ANOVA.* P < 0.05 vs. PBS control. # P < 0.05 vs. NC8 control