Skip to main content
Fig. 3 | Microbial Cell Factories

Fig. 3

From: Effective treatment of hypertension by recombinant Lactobacillus plantarum expressing angiotensin converting enzyme inhibitory peptide

Fig. 3

Change of systolic blood pressure (SBP) after oral administration of recombinant Lb. plantarum NC8 (RLP) strain in spontaneously hypertensive rat. The rats were treated orally with either RLP or Lb. plantarum NC8 (NC8) at a dose of 2 × 1011 CFU for 14 continuous days, whereas additional PBS-treated rats were included as controls. The SBP was continuously determined during the first 15 days and then at day 19 and day 24 as described in the methods section. The statistical significance was calculated by one-way ANOVA test. *P < 0.05; **P < 0.01 vs. PBS control

Back to article page