Skip to main content

Table 1 Biotransformation of 1,3PDO by G. oxydans at 28 °C and 800 rpm for 3 h

From: Bio-based 3-hydroxypropionic- and acrylic acid production from biodiesel glycerol via integrated microbial and chemical catalysis

Biocatalyst (mg/mL) Alcohol dehydrogenase reaction (ADH) Aldehyde dehydrogenase reaction (ALDH) 3HP Yield d mol% (24 h)
1,3PDO (mg/mL) Remaining 1,3PDO (mg/mL) Conversiona (%) Substrateb (mg/mL) 3HPA (mg/mL) 3HP (mg/mL) Conversionc (%)
5.2 5 0.2 95.3 4.6 0.2 5.4 95.0 95.4
5.2 10 1.4 86.1 8.4 0.1 10.1 98.9 96.9
5.2 15 7.7 48.7 7.1 0.1 8.6 99.1 97.1
5.2 20 13.7 31.3 6.1 0.1 7.3 98.6 96.6
5.2 25 18.9 24.5 6.0 1.4 5.5 76.0 98.5
5.2 30 24.8 17.2 5.0 1.6 4.2 68.0 98.3
2.6 10 4.5 54.9 5.4 0.0 6.5 99.7 98.5e
3.9 10 2.4 75.7 7.4 0.1 8.9 99.0 97.8e
6.5 10 2.0 80.2 7.8 0.2 9.3 98.1 95.8e
  1. 1,3PDO 1,3-propanediol, 3HPA 3-hydroxypropionaldehyde, 3HP 3-hydroxypropionic acid
  2. aConversion of 1,3PDO
  3. bSubstrate calculated as the sum of 3HPA and 3HP used in the ALDH reaction (converted to 3HPA equivalent)
  4. cConversion of 3HPA to 3HP
  5. dOverall yield (mol%) of 3HP from 1,3PDO after 24 h
  6. ecalculated after 12 h