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Fig. 2 | Microbial Cell Factories

Fig. 2

From: Genome-scale metabolic reconstructions and theoretical investigation of methane conversion in Methylomicrobium buryatense strain 5G(B1)

Fig. 2

Possible modes of methane oxidation for methane-grown M. buryatense 5GB1. Upper panel a genome scale FBA was used to test three possible modes of methane oxidation: a redox-arm mode, the currently accepted model in which electrons driving methane oxidation come from NADH produced by formate or formaldehyde oxidation, while electrons produced from methanol oxidation are linked to a redox-arm and used for ATP production (adapted from Semrau et al. [30]); b direct coupling mode, in which methanol oxidation supplies electrons for methane oxidation; and c uphill electron transfer model, in which methanol oxidation partially supports methane oxidation (from [18]). Proton translocation and ATP synthesis were omitted for simplicity. P periplasm, L ICM (lumen), C cytoplasm

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