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Table 1 Summary of 1H and 13C NMR data for compound 1 and compound 2 in CDCl3

From: Identification of novel tylosin analogues generated by a wblA disruption mutant of Streptomyces ansochromogenes

Position Compound 1 Compound 2
δ (1H, mult., J) 13C (δ) δ (1H, mult., J) 13C (δ)
1   174.7   174.7
2 1.92 (1H, d, 16) 2.5 (1H, dd, 17, 10.7) 39.2 1.92 (1H, d, 16) 2.5 (1H, dd, 17, 10.7) 39.2
3 3.72 (1H, d, 10.0) 67.1 3.72 (1H, d, 10.0) 66.8
4 1.48 (1H, *) 39.9 1.48 (1H, *) 39.9
5 4.1 (1H, d, 13.0) 71.6 3.77 (1H, d, 9.0) 72.6
6 4.3 (1H, *) 67.9 1.3 (1H, *) 38
7 2.0 (1H, m) 1.56 (1H, *) 29.2 1.42 (1H, m) 1.57 (1H, *) 32.7
8 2.8 (1H, br) 45.1 2.7 (1H, br) 45.1
9   204   204
10 6.34 (1H, d, 15.0) 118.3 6.33 (1H, d, 15.0) 118.6
11 7.32 (1H, d, 15.0) 148.1 7.32 (1H, d, 15.0) 147.8
12   135.1   135.5
13 5.92 (1H, d, 10.0) 141.9 5.92 (1H, d, 10.0) 141.7
14 2.98 (1H, m) 45.1 2.98 (1H, m) 45.1
15 4.98 (1H, ddd, 10.0, 10.0, 2.0) 75.3 4.98 (1H, ddd, 10.0, 10.0, 2.0) 75.2
16 1.88 (1H, m) 1.63 (1H, *) 25.4 1.88 (1H, m) 1.63 (1H,*) 25.5
17 0.94 (3H, *) 9.5 0.94 (3H, *) 9.5
18 1.0 (3H, d, 6.0) 9.5 1.0 (3H, d, 6.0) 9.6
19 1.22 (3H, d, 7.0) 17.6 1.62 (1H, *) 1.3 (1H, *) 22.7
20 1.81 (3H, s) 13.2 0.92 (3H, *) 9.4
21 4.01 (1H, dd, 9.0, 4.0) 3.55 (1H, *) 69.1 1.23 (3H, d,7.0) 17.6
22    1.81 (3H, s) 13.2
23    4.01 (1H, dd, 9.0, 4.0) 3.55 (1H, *) 69
1` 4.58 (1H, d, 7.5) 101.1 4.58 (1H, d, 7.5) 101.1
2` 3.04 (1H, dd, 7.5, 2.5) 81.5 3.04 (1H, dd, 7.5, 2.5) 81.5
3` 3.77 (1H, d, 9.0) 79.8 3.77 (1H, d, 9.0) 79.8
4` 3.2 (1H, m) 72.6 3.2 (1H, m) 72.6
5` 3.53 (1H, *) 70.5 3.53 (1H, *) 70.5
6` 1.29 (3H, *) 17.7 1.29 (3H, *) 17.7
7` 3.5 (3H, s) 59.7 3.5 (3H, s) 59.7
8` 3.63 (3H, s) 61.9 3.63 (3H, s) 61.9
  1. In this table, s singlet, d doublet, m multiplet, br broad
  2. * Overlapping with other signals