Fig. 6
From: Metabolomics investigation of recombinant mTNFα production in Streptomyces lividans
The relative peak areas (box plots) of the significant metabolites identified by CPCA-W of cell extracts and footprints GC–MS data are plotted onto the metabolic map of S. lividans TK24. Different colours of the box plots indicate different strains, wild (W, red), empty plasmid (E, green) and mTNFα-producer (T, blue). While the numbers 1–4 represent separate sampling time points, 24, 48, 72 and 96 h respectively. Different coloured arrows represent the potential contribution of each substrate towards various metabolites and pathways